Important Safety Information

NAD+ Therapy

Important Safety Information for NAD+ Therapy

This information is not a substitute for the advice of a licensed healthcare professional. Treatment eligibility, formulation, route of administration, dose, frequency, monitoring, and duration are determined by the prescribing Provider based on individual medical circumstances. Use medication only as prescribed and follow the label and pharmacy instructions.

Emergency Warning

Call 911 or seek emergency medical care immediately for trouble breathing; swelling of the face, lips, tongue, or throat; severe chest pain; fainting; seizure; sudden weakness or confusion; signs of a severe allergic reaction; or any other severe or rapidly worsening symptom.

What Is NAD+

Nicotinamide adenine dinucleotide ("NAD+") is a naturally occurring coenzyme involved in cellular metabolism. NAD+ products offered through the services may be compounded for an individual patient pursuant to a prescription. The clinical evidence supporting many promoted uses of compounded NAD+ is limited, and no particular benefit or outcome is guaranteed.

Compounded Medication Notice

Compounded drugs are not approved by the U.S. Food and Drug Administration ("FDA"). The FDA does not verify the safety, effectiveness, quality, or labeling of compounded drugs before they are marketed. A Provider may prescribe a compounded medication when the Provider determines that a compounded preparation is clinically appropriate for an identified patient. Compounded medications may differ in formulation, concentration, excipients, route, and storage requirements by pharmacy.

Do Not Use or Tell Your Provider Before Use

Do not begin or continue NAD+ therapy without discussing all medical conditions, medications, supplements, allergies, and prior reactions with your Provider. Tell your Provider before use if you:

• Are pregnant, trying to become pregnant, or breastfeeding.
• Have a known allergy or prior reaction to NAD+, niacin-related compounds, preservatives, diluents, or any ingredient in the dispensed product.
• Have significant kidney, liver, cardiovascular, neurologic, metabolic, bleeding, or other chronic disease.
• Have an active infection, fever, dehydration, or uncontrolled medical condition.
• Have a history of fainting, severe injection reactions, or difficulty safely administering injections.
• Take prescription drugs, over-the-counter drugs, vitamins, herbs, or supplements, because interaction data may be limited.
• Are scheduled for surgery or another procedure.

Possible Risks and Side Effects

Side effects may vary by formulation and route. Report persistent, severe, or concerning symptoms to your Provider. Potential risks may include:

• Injection-site pain, redness, warmth, swelling, itching, bruising, bleeding, induration, or infection.
• Nausea, abdominal discomfort, diarrhea, reduced appetite, or other gastrointestinal symptoms.
• Headache, dizziness, flushing, sweating, fatigue, restlessness, or changes in sleep.
• Muscle cramping, chest tightness, palpitations, shortness of breath, or changes in blood pressure.
• Allergic or hypersensitivity reactions, including rare severe reactions.
• Medication errors, contamination, potency variation, or other quality risks associated with compounded preparations.
• Unknown risks, including unknown long-term effects and risks not yet identified in clinical studies.

Administration Safety

• Use the exact dose, route, frequency, syringe, needle, and technique prescribed or provided by the pharmacy.
• Do not share medication, needles, syringes, alcohol pads, or other injection supplies.
• Wash your hands and use a clean preparation area. Inspect the vial or syringe before each use.
• Do not use medication that is expired, improperly stored, leaking, cracked, discolored, cloudy when it should be clear, contains unexpected particles, or otherwise appears abnormal. Contact the dispensing pharmacy.
• Rotate injection sites as instructed. Do not inject into skin that is tender, bruised, red, hard, scarred, infected, or otherwise abnormal.
• Use a new sterile needle and syringe for each injection. Dispose of used sharps immediately in an FDA-cleared sharps container or another container permitted by local requirements.
• Do not change the dose or frequency or combine the medication with another product unless specifically directed by your Provider.

Storage and Handling

Follow the dispensing pharmacy label exactly. Storage requirements may vary by formulation. Keep medication and supplies out of the reach of children and pets. Do not freeze unless the pharmacy specifically instructs you to do so. Protect the product from heat, moisture, and light as directed. Contact the pharmacy if medication experiences a temperature excursion or arrives damaged.

Missed Dose, Overdose, or Administration Error

Do not double a dose unless your Provider expressly instructs you to do so. Contact your Provider or dispensing pharmacy for instructions after a missed dose or administration error. For suspected overdose or a serious reaction, call 911 or Poison Control at 1-800-222-1222.

Monitoring and Follow-Up

Complete all follow-up questionnaires, visits, laboratory testing, and monitoring requested by your Provider. Promptly report new symptoms, medication changes, pregnancy, emergency care, hospitalization, or a new diagnosis. A Provider may modify, pause, or discontinue treatment at any time based on safety, effectiveness, adherence, availability, or clinical judgment.

No Guarantee of Results

Individual responses vary. Atelier Protocol LLC, Wasef Health, PC, Providers, and pharmacy partners do not guarantee weight change, energy, longevity, cognitive, athletic, metabolic, anti-aging, or other outcomes from NAD+ therapy.

Questions

Clinical questions: contact your Provider through the secure patient channel.
Medication quality, storage, or shipping questions: contact the dispensing pharmacy listed on the medication label.
Administrative support: care@atelierprotocol.com or (929) 723-3212.